Blastic plasmacytoid dendritic cell neoplasm: a single-center experience
AbstractBlastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive hematologic malignancy originating from the precursor of the plasmacytoid dendritic cell. It is very rare and has only...
View ArticleTotal intraglandular and index tumor volumes predict biochemical recurrence...
AbstractPrognostic value of tumor volume for biochemical recurrence of prostate cancer remains controversial. We aimed to determine which tumor volume definition would optimally correlate with...
View ArticlePI-RADS version 2: quantitative analysis aids reliable interpretation of...
AbstractObjectivesTo determine whether apparent diffusion coefficient (ADC) ratio aids reliable interpretation of diffusion-weighted imaging (DWI) for prostate cancer (PCa).MethodsSeventy-six...
View ArticleNon-contrast magnetic resonance imaging for bladder cancer: fused high b...
AbstractObjectsTo investigate the utility of fused high b value diffusion-weighted imaging (DWI) and T2-weighted imaging (T2WI) for evaluating depth of invasion in bladder cancer.MethodsWe included 62...
View ArticleSingle-stranded DNA binding protein 2 expression is associated with patient...
AbstractBackgroundSSBP2, single-stranded DNA binding protein 2, is a subunit of the ssDNA-binding complex that is involved in the maintenance of genome stability. The majority of previous studies have...
View ArticleClinicopathologic features of rheumatoid nodules: a retrospective analysis
AbstractObjectivesThe clinical and histopathologic features of patients that have been diagnosed with rheumatoid nodules were investigated.MethodsThis study included patients with rheumatoid nodules,...
View ArticleDiscrimination of HPV status using CT texture analysis: tumour heterogeneity...
AbstractPurposeTo evaluate the diagnostic performance of texture analysis for discriminating human papillomavirus (HPV) status in patients with oropharyngeal squamous cell carcinoma (OPSCC) in the...
View ArticleImproving counterfire operations with enhanced command and control structure
AbstractThe success of military operations depends on soldiers’ execution of the operation as well as resources used for the operation. However, this does not mean that more men and firepower will...
View ArticleHigh CD3 and ICOS and low TIM-3 expression predict favourable survival in...
AbstractWith the increasing oncological potential of immunotherapy, several immune checkpoint modulators are being investigated. The value of immune markers, including programmed cell death ligand-1,...
View ArticleUtilization potential of intraluminal optical coherence tomography for the...
AbstractImaging the Eustachian tube is challenging because of its complex anatomy and limited accessibility. This study fabricated a fiber-based optical coherence tomography (OCT) catheter and...
View ArticlePrevalence of cancer susceptibility variants in patients with multiple Lynch...
AbstractAlong with early-onset cancers, multiple primary cancers (MPCs) are likely resulting from increased genetic susceptibility; however, the associated predisposition genes or prevalence of the...
View ArticleClinicopathologic and genomic characteristics of mucinous gastric adenocarcinoma
AbstractBackgroundMucinous gastric adenocarcinoma (MGC) is a rare but distinctive histologic subtype of gastric cancer (GC). The clinico-pathologic and genomic characteristics of MGC have not been well...
View ArticleWnt/β-catenin pathway is a key signaling pathway to trastuzumab resistance in...
AbstractBackgroundTrastuzumab is the only approved target agent for the first-line treatment of human epidermal growth factor receptor-2 (HER-2) positive gastric cancer; however, trastuzumab resistance...
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Phonozen-mediated photodynamic therapy comparing two wavelengths in a mouse...
AbstractBackgroundThis study assessed the therapeutic efficacy of intraperitoneal photodynamic therapy (PDT) using photosensitizer activation at two different wavelengths, 405 and 664 nm, in a mouse...
View ArticleGenomic and evolutionary characteristics of metastatic gastric cancer by routes
AbstractBackgroundIn gastric cancer (GC) patients, metastatic progression through the lymphatic, hematogenous, peritoneal, and ovarian routes, is the ultimate cause of death. However, the genomic and...
View ArticleFrequency of GNAS R201H substitution mutation in polyostotic fibrous...
AbstractGuanine nucleotide-binding protein/α-subunit (GNAS) mutations are involved in fibrous dysplasia (FD) pathogenesis. Here, we analyzed GNAS mutations in FD which were performed by pyrosequencing...
View ArticleHoxB13 expression in ductal type adenocarcinoma of prostate:...
AbstractThe histologic criteria and selective biomarkers of prostate ductal type adenocarcinoma (DAC) are relatively unknown compared to that known about acinar type adenocarcinoma (AAC). It is known...
View ArticleYet Another Automated Gleason Grading System (YAAGGS) by weakly supervised...
AbstractThe Gleason score contributes significantly in predicting prostate cancer outcomes and selecting the appropriate treatment option, which is affected by well-known inter-observer variations. We...
View ArticleA single arm phase Ib/II trial of first-line pembrolizumab, trastuzumab and...
AbstractIn this multi-center phase II trial, we evaluated the efficacy and safety of a quadruplet regimen (pembrolizumab, trastuzumab, and doublet chemotherapy) as first-line therapy for unresectable...
View ArticleDurvalumab plus pazopanib combination in patients with advanced soft tissue...
AbstractWe aimed to determine the activity of the anti-VEGF receptor tyrosine-kinase inhibitor, pazopanib, combined with the anti-PD-L1 inhibitor, durvalumab, in metastatic and/or recurrent soft tissue...
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